Weilian Yang Selected Research

Boron

1/2018	Boron delivery agents for neutron capture therapy of cancer.
7/2016	Targeting glioma stem cells enhances anti-tumor effect of boron neutron capture therapy.
6/2014	Evaluation of unnatural cyclic amino acids as boron delivery agents for treatment of melanomas and gliomas.
6/2014	Effects of l-DOPA pre-loading on the uptake of boronophenylalanine using the F98 glioma and B16 melanoma models.
1/2013	Biodistribution and subcellular localization of an unnatural boron-containing amino acid (cis-ABCPC) by imaging secondary ion mass spectrometry for neutron capture therapy of melanomas and gliomas.
12/2011	Boronated unnatural cyclic amino acids as potential delivery agents for neutron capture therapy.
6/2011	Convection enhanced delivery of carboranylporphyrins for neutron capture therapy of brain tumors.
12/2009	Convection enhanced delivery of boronated EGF as a molecular targeting agent for neutron capture therapy of brain tumors.
2/2008	Molecular targeting and treatment of composite EGFR and EGFRvIII-positive gliomas using boronated monoclonal antibodies.
2/2007	Molecular targeting and treatment of an epidermal growth factor receptor-positive glioma using boronated cetuximab.

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Weilian Yang Research Topics

Disease

30	Glioma (Gliomas) 09/2020 - 06/2002
30	Neoplasms (Cancer) 01/2018 - 03/2002
19	Brain Neoplasms (Brain Tumor) 01/2016 - 03/2002
5	Experimental Melanoma 01/2015 - 12/2011
5	Melanoma (Melanoma, Malignant) 06/2014 - 03/2002
1	Poisoning 01/2022
1	Leukemia 01/2012
1	Glioblastoma (Glioblastoma Multiforme) 02/2011
1	Hypoxia (Hypoxemia) 07/2009
1	Carcinoma (Carcinomatosis) 07/2003
1	Gliosarcoma 03/2003
1	Body Weight (Weight, Body) 03/2003
1	Sarcoma (Soft Tissue Sarcoma) 01/2003

Drug/Important Bio-Agent (IBA)

19	BoronIBA 01/2018 - 03/2002
8	ErbB Receptors (EGF Receptor)IBA 01/2016 - 06/2002
7	Epidermal Growth Factor (EGF)IBA 12/2009 - 06/2002
5	ThymidineIBA 12/2015 - 09/2004
5	Dendrimers (Dendrons)IBA 12/2009 - 11/2002
5	Cetuximab (Erbitux)FDA Link 02/2008 - 01/2004
5	Monoclonal AntibodiesIBA 02/2008 - 11/2004
4	Carboplatin (JM8)FDA LinkGeneric 09/2020 - 02/2011
4	thymidine kinase 1IBA 12/2015 - 09/2004
4	epidermal growth factor receptor VIIIIBA 02/2008 - 01/2004
3	Cisplatin (Platino)FDA LinkGeneric 09/2020 - 01/2012
3	4-boronophenylalanineIBA 06/2014 - 12/2011
3	AcidsIBA 06/2014 - 12/2011
3	Mannitol (Osmitrol)FDA LinkGeneric 01/2014 - 03/2002
3	Biological ProductsIBA 09/2006 - 03/2003
2	EnzymesIBA 12/2015 - 07/2015
2	NucleosidesIBA 07/2015 - 09/2004
2	Amino Acids FDA Link 01/2013 - 12/2011
2	Liposomes (Liposome)IBA 01/2012 - 07/2003
2	Pharmaceutical PreparationsIBA 12/2011 - 03/2003
2	SodiumIBA 12/2011 - 03/2003
2	Folic Acid (Vitamin M)FDA LinkGeneric 07/2003 - 01/2003
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	Peptides (Polypeptides)IBA 01/2016
1	Thymidine KinaseIBA 07/2015
1	pyrimidineIBA 07/2015
1	PlatinumIBA 01/2015
1	Cyclic Amino AcidsIBA 06/2014
1	Levodopa (L Dopa)FDA LinkGeneric 06/2014
1	Furosemide (Lasix)FDA LinkGeneric 01/2014
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2014
1	Amino Acid Transport Systems (Amino Acid Transporter)IBA 01/2013
1	Protein Kinase CIBA 01/2012
1	PorphyrinsIBA 06/2011
1	A 7 (A-7)IBA 12/2009
1	Contrast MediaIBA 07/2009
1	ferric oxide (iron oxide)IBA 07/2009
1	NitroimidazolesIBA 07/2009
1	ferumoxtran-10 (ultrasmall superparamagnetic iron oxide)IBA 07/2009
1	Methotrexate (Mexate)FDA LinkGeneric 01/2006
1	Nucleic Acid PrecursorsIBA 09/2004
1	Messenger RNA (mRNA)IBA 03/2003
1	Poly(amidoamine)IBA 01/2003
1	Ethylene Glycol (Monoethylene Glycol)IBA 01/2003
1	RMP 7IBA 03/2002
1	SolutionsIBA 03/2002

Therapy/Procedure

14	Boron Neutron Capture Therapy 07/2016 - 11/2002
13	Neutron Capture Therapy 01/2018 - 03/2002
6	Radiotherapy 09/2020 - 03/2003
5	Therapeutics 01/2022 - 01/2005
1	Drug Therapy (Chemotherapy) 07/2016
1	Euthanasia (Mercy Killing) 07/2009
1	Injections 11/2008
1	Nuclear Reactors 02/2008